Mendelian randomization analysis of blood metabolites and immune cell mediators in relation to GVHD and relapse.

The pathway analyses mainly included two libraries, the Small Molecule Pathway Database (SMPDB) [ 57 ] and the KEGG [ 29 ] database, and the significance level of the pathway analysis was nominally significant, i.e., P < 0.05.

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Although the differences in other comparisons did not reach statistical significance, pyridoxine levels were almost higher in the non-aGVHD group, while both glycochenodeoxycholic acid 7-sulfate and glycochenodeoxycholic acid 3-glucuronide tended to be elevated in the aGVHD group.

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