Grid-based transcutaneous spinal cord stimulation: probing neuromodulatory effect in spinal flexion reflex circuits.

Nevertheless, when statistically examined, the trending level of inhibition observed with scapular stimulation, while statistically insignificant, was significantly smaller in AUC difference compared to when the grid was applied over the site of interest on the spine for the DIAG configuration [ F (1, 237) = 12.6, p < 0.001], with a trend toward significance in latency [ F (1, 235) = 3.125, p = 0.078].

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Additionally, while the latency of the flexion reflex remained consistent across all stimulation conditions, an increasing trend was observed specifically in the DIAG condition.

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Specifically, latency remained unchanged for the TRS [ F (1, 14.6) = 0.396, p = 0.539], DIAG [ F (1, 16.8) = 3.22, p = 0.091], or Sham condition [ F (1, 12.3) = 1.01, p = 0.335], while the DIAG condition showed a trend toward increased latency.

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The neuromodulatory effect on the Sol H max / M max ratio did not reach statistical significance for either grid.

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