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Roles of MASP-1 and MASP-3 in the development of retinal degeneration in a murine model of dry age-related macular degeneration.

Front Immunol · 2025 · PMC11985759 · PMID 40226626

2
hedged sentences
0.1290
closest p · 2.6× alpha
0.1290
boldest claim

The sentences

did not reach statistical significanceP = 0.129not close (p > 0.1)
There was a trend toward lower iC3b levels in the lysates from MASP-1 -/- mice compared to those from WT mice, although the difference between MASP-1 -/- and WT mice did not reach statistical significance (P = 0.129, Figure 4D ).

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showed a trendno p-value reported
Only MASP-3 -/- mice showed statistically significant decrease in the percentage of necrotic RPE area compared to WT mice, however, both MASP-1 -/- and MASP-1/3 -/- mice also showed a trend toward smaller necrotic RPE area than WT mice 7 d after NaIO 3 injection.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.