There was a trend toward lower iC3b levels in the lysates from MASP-1 -/- mice compared to those from WT mice, although the difference between MASP-1 -/- and WT mice did not reach statistical significance (P = 0.129, Figure 4D ).
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Roles of MASP-1 and MASP-3 in the development of retinal degeneration in a murine model of dry age-related macular degeneration.
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0.1290
The sentences
Only MASP-3 -/- mice showed statistically significant decrease in the percentage of necrotic RPE area compared to WT mice, however, both MASP-1 -/- and MASP-1/3 -/- mice also showed a trend toward smaller necrotic RPE area than WT mice 7 d after NaIO 3 injection.