Exploring the neuromagnetic signatures of cognitive decline from mild cognitive impairment to Alzheimer's disease dementia.

However, this result should be interpreted with caution as we discuss subtle patterns of spatially averaged spectral metrics that did not reach statistical significance, unlike the MANOVA results which made better use of the spatial information to detect altered frequency ranges but did not provide topographic readouts.

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Likewise, spatio-spectral cluster testing topographical maps showed a trend towards decreased spectral power from 14.4Hz to 25Hz in the posterior regions in the AD progression group using a p-value threshold below 0.10.

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Of note, the choice of a nominal alpha level can seem particularly arbitrary in the context of a ML model as performance drops that are not statistically significant may still be economically or practically significant.

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