Extracellular Vesicle-Liposome-Darunavir Formulation for the Treatment of HIV Neuropathogenesis.

ACS Appl Nano Mater · 2025 · PMC11997951 · PMID 40242041

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showed a trendno p-value reported

Discrimination index (DI): both DRV and EV-Lip-DRV treatments, via IP and IN routes, showed a trend in improved DI in HIV-infected mice, aligning the DI values closer to those of the non-HIV control group, but not statistically significant.

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did not reach statistical significanceno p-value reported

Similarly, in the lungs, there was a trend toward higher DRV concentration in the EV-Lip-DRV group via the IN group, though this did not reach statistical significance.

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