Barely Significant
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Impact of age, HIV1, sickle-cell genotypes, and interferon-gamma gene upstream variants on malaria disease outcomes in a longitudinal pediatric cohort.

Sci Rep · 2025 · PMC12000329 · PMID 40234522

2
hedged sentences
0.0910
closest p · 1.8× alpha
0.0910
boldest claim

The sentences

did not reach statistical significanceP = 0.091so close (0.05 < p ≤ 0.1)
There was also a 37.2% hazard of longitudinal malaria episodes in carriers of the GG/TA diplotype, but the results did not reach statistical significance [0.628 (0.403–0.979), P = 0.091].

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showed a trendno p-value reported
While the GA/GG diplotype showed a trend toward fewer SMA events (33.5%), the lack of statistical significance indicates that this diplotype may not have a strong protective effect.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.