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Improving ototoxicity monitoring in patients receiving aminoglycosides using a novel digital approach: a quality improvement project.

BMJ Open Qual · 2025 · PMC12001346 · PMID 40233985

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approached significanceno p-value reported
41 Age (also shown by Sturdy et al ) and pre-existing hearing loss within 0.25–8 kHz frequencies approached significance for ototoxicity, highlighting that concomitant use of IVAGs with current hearing impairment caused by presbycusis, or otherwise, could potentially exacerbate hearing loss and should be a consideration when prescribing IVAGs. 42 Lessons learnt The aim of the quality improvement project was to improve IVAG ototoxicity monitoring in a centre with no on-site and no prior audiology services.

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The OMP service was reduced during the COVID-19 pandemic, restricting clinical activities to essential work only, negatively impacting numbers of patients that received both baseline and end-of-course tests, which fell from 63% to 43% (p=0.62) in month 6 and from 67% to 14% (p=0.057) in month 8 trending towards significance in the latter approaching the winter months but also coinciding with reduced OMP staff.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.