Enhancing the effects of nusinersen with cybernic treatment using Hybrid Assistive Limb (HAL) in spinal muscular atrophy: a real-world case series and exploratory cohort analysis.

Orphanet J Rare Dis · 2025 · PMC12020134 · PMID 40270050

Europe PMC DOI

hedged sentences

0.0940

closest p · 1.9× alpha

0.0940

boldest claim

The sentences

did not reach statistical significancep = 0.094so close (0.05 < p ≤ 0.1)

Despite observed improvements in 2MWT in Cohort 1 at 15 months, the between-group difference in 2MWT did not reach statistical significance ( p = 0.094).

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showed a trendno p-value reported

RULM total scores showed a trend towards improvement from baseline at 15 months in Cohort 1, but not in Cohort 2.

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