Preclinical validation of TGFβ inhibitors as a novel therapeutic strategy for post-traumatic heterotopic ossification.

In addition, SIS3 showed a trend towards a lower extent of HO formation following all doses in the 1 week + 2 weeks timepoint and following medium and high doses at the 1 month + 1.5 months, 2 months + 2.5 months, and 3 months + 3.5 months timepoints.

also in 53,322 other papers

In addition, the expression of the osteogenic markers Alp and Runx2 was investigated by q-RT-PCR, however, while downregulation was observed in some of the treatment conditions these results did not reach statistical significance.

also in 111,027 other papers