Metabolomic signatures of cognitive function in a type 2 Diabetes-Enriched cohort.

Sci Rep · 2025 · PMC12033351 · PMID 40287557

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

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boldest claim

The sentences

nominally significantP < 0.05actually significant

For cross-ancestry comparison of significant hits in the discovery phase, a nominally significant threshold of P < 0.05 was considered significant.

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did not reach statistical significanceno p-value reported

Three metabolites were associated with 3MSE in the AA discovery sample; however, only one metabolite (X-18901) was directionally consistent but did not reach statistical significance in the replication or overall meta-analysis ( ST21 ).

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