Migraine and increased cardiovascular disease risk: interaction with traditional risk factors and lifestyle factors.

J Headache Pain · 2025 · PMC12036269 · PMID 40295899

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did not reach statistical significanceno p-value reported

However, the interactions between migraine and the degree of traditional risk factor control did not reach statistical significance.

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a significant trendno p-value reported

In a thoroughly adjusted analysis, individuals with migraine demonstrated an increased risk of atherosclerotic cardiovascular disease, with a hazard ratio of 1.12 (95% confidence interval: 1.05 to 1.20) compared to those without migraine, indicating a significant trend (P FDR < 0.001).

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