Impact of Post Percutaneous Coronary Intervention Fractional Flow Reserve on 5-Year Clinical Outcomes (The FFR SEARCH Study).

However, the recently presented 3‐year results showed a significantly lower TVR rate (62% reduction) in the IVUS‐guided optimization arm and a strong trend toward lower TVF rates, indicating a more important long‐term effect of post‐PCI FFR and optimization [ 19 ].

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That said, the unadjusted and adjusted HRs describing the event risk were numerically comparable with the results of the main analysis, but did not reach statistical significance, likely due to a loss of sample size.

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