Barely Significant
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HIV-Tat upregulates the expression of senescence biomarkers in CD4<sup>+</sup> T-cells.

Front Immunol · 2025 · PMC12058733 · PMID 40342418

Europe PMCDOI
2
hedged sentences
0.0769
closest p · 1.5× alpha
0.1796
boldest claim

The sentences

showed a trendp=0.0769so close (0.05 < p ≤ 0.1)
All experiments showed a trend towards a reduced expression of Ki-67 in Tat 101 cells, compared to Tet off (p=0.0769) ( Figure 1E ).

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did not reach statistical significancep=0.1796not close (p > 0.1)
We also detected a marginal increase in BCL2 ( Figure 5E ), and a decrease in CD4 expression ( Figure 5F ) in FLAG + cells compared to their FLAG - counterparts, but these changes did not reach statistical significance (p=0.1796 and p= 0.2104, respectively).

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