Deciphering ERR family genes as prognostic and immunological biomarkers through pan-cancer analysis with validation in gallbladder cancer.

Front Oncol · 2025 · PMC12066295 · PMID 40356747

Europe PMC DOI

hedged sentences

0.0650

closest p · 1.3× alpha

0.0650

boldest claim

The sentences

did not reach statistical significancep = 0.065so close (0.05 < p ≤ 0.1)

The analysis of Kaplan-Meier survival indicated that positive ESRRG expression correlates with poor PFS ( Figure 4D , p < 0.01).Although ESRRG expression showed a negative correlation with poorer OS ( Figure 4D ), this association did not reach statistical significance (p = 0.065), suggesting that ESRRG may play a more critical role in tumor recurrence and metastasis.

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showed a trendno p-value reported

Importantly, all of the three subfamily genes showed a trend toward positive correlation with advanced tumors in CHOL.

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