Barely Significant
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High bicarbonate replacement fluid and time to pH normalization during continuous veno-venous hemofiltration with regional citrate anticoagulation: a retrospective single-center cohort study.

Clin Kidney J · 2025 · PMC12067065 · PMID 40357503

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showed a trendno p-value reported
S3 and showed a trend towards higher values over time.

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The SAPS 3 was higher in patients with acidemia (acidemia: 79 vs alkalemia: 69 vs normal pH: 74), although this difference did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.