Aging-Associated Liver Sinusoidal Endothelial Cells Dysfunction Aggravates the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease.

Likewise, the spleen/body weight ratios were higher in the MASH rats as compared to the age‐matched control rats albeit did not reach statistical significance; however, an age‐related increment was observed in spleen/body weight ratio for both control and MASH cohorts (Figure 3B ).

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Moreover, Y‐MASH rats depicted a strong trend of higher HAR than A‐MASH rats both without and with L‐NMMA (Figure 6G,H ).

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