Barely Significant
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Does Pre-Existing Chronic Obstructive Pulmonary Disease Increase the Risk of Checkpoint Inhibitor Pneumonitis in Advanced/Metastatic Non-Small Cell Lung Cancer Treated with Immune Checkpoint Inhibitors?

Curr Oncol · 2025 · PMC12110116 · PMID 40422518

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showed a trendno p-value reported
The presence of COPD showed a trend toward increased risk; however, the confidence interval was wide (0.92–4.68), and the p -value did not reach statistical significance (0.079). 4.

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