Association of CETP, APOA5, IL6, and PON1 Gene Variants with Dyslipidemia and Cardiovascular Risk in a Population from Cauca Department, Colombia.

Genes (Basel) · 2025 · PMC12111601 · PMID 40428368

Europe PMC DOI

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closest p · 1.0× alpha

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boldest claim

The sentences

did not reach statistical significancep > 0.05actually significant

In contrast, BMI, systolic blood pressure, body fat percentage, ethnicity, and educational level did not reach statistical significance ( p > 0.05) and, thus, do not independently predict dyslipidemia in this model.

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failed to reach statistical significanceno p-value reported

Similarly, the CA genotype exhibited an OR of 1.257, which also failed to reach statistical significance.

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highly significantno p-value reported

Total cholesterol maintained its inverse association (OR = 0.944, 95% CI 0.919, 0.970, p < 0.001), while HDL (OR = 0.651, 95% CI 0.472, 0.898, p = 0.009), triglycerides (OR = 2.568, 95% CI 1.734, 3.804, p < 0.001), and VLDL (OR = 0.878, 95% CI 0.795, 0.971, p = 0.011) all remained highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Association of &lt;i&gt;CETP&lt;/i&gt;, &lt;i&gt;APOA5&lt;/i&gt;, &lt;i&gt;IL6&lt;/i&gt;, and &lt;i&gt;PON1&lt;/i&gt; Gene Variants with Dyslipidemia and Cardiovascular Risk in a Population from Cauca Department, Colombia.

The sentences

Association of <i>CETP</i>, <i>APOA5</i>, <i>IL6</i>, and <i>PON1</i> Gene Variants with Dyslipidemia and Cardiovascular Risk in a Population from Cauca Department, Colombia.