Artemisinin derivatives differently affect cell death of lung cancer subtypes by regulating GPX4 in patient-derived tissue cultures.

CTR)) as well as a clear trend towards enhanced GPX4 expression was observed with ATS (median: 270% (20 μM)).

also in 8,934 other papers

Median values of the lower concentrations ( n = 9–11) showed an elevated trend in comparison to the control condition (DHA: 131%,10 μM; ATS: 137%, 20 μM; ART: 103%, 100 μM; ATM: 121%, 50 μM) while the higher concentrations ( n = 4) do not show elevated fractions of tumor apoptosis (DHA: 77%,30 μM; ATS: 104%, 40 μM; ART: 54%, 200 μM; ATM: 72%, 100 μM Fig. 1B ).

also in 145 other papers

Although tumor cell apoptosis did not reach statistical significance, three PDTC did show robust alterations when supplemented with DHA and ATS.

also in 53,799 other papers