Behavioral and emotional difficulties in maltreated children: Associations with epigenetic clock changes and visual attention to social cues.

PLoS One · 2025 · PMC12124526 · PMID 40445999

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0820

boldest claim

The sentences

approached significanceP = 0.056so close (0.05 < p ≤ 0.1)

In this model, the path from group to mAge acceleration approached significance (a 1 = 0.35, SE = 0.18, P = 0.056), as did the path from mAge to visual attention to the eyes (a 2 = -0.06, SE = 0.03, P = 0.042).

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showed a trendP = 0.08so close (0.05 < p ≤ 0.1)

Post-hoc analysis using Tukey’s honest significance test (HSD) revealed that CM exposed to three types of maltreatment had significantly higher SDQ total scores than those exposed to one type ( P = 0.03) and showed a trend toward higher scores than those exposed to two types ( P = 0.08).

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tendency toward significanceP = 0.082so close (0.05 < p ≤ 0.1)

The paths to SDQ total scores from mAge acceleration and visual attention to the eyes also showed a tendency toward significance (b 1 = 1.23, SE = 0.71, P = 0.082; b 2 = -8.08, SE = 4.33, P = 0.062), along with a direct path from group to SDQ total scores [c = 4.566, SE = 1.13, P = 5.12e-05, and c’ = 3.60, SE = 1.11, P = 1.21e-03].

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