Positive Margin Rates After Breast-Conserving Surgery by Histologic Subtype: A Systematic Review and Meta-analysis Evaluating the Impact of Oncoplastic Surgery.

Ann Surg Oncol · 2025 · PMC12129873 · PMID 40272667

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an interesting trendno p-value reported

43 Despite this clearly elevated risk of positive margins for ILC, our findings also showed an interesting trend in outcomes when utilizing oncoplastic BCS.

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did not reach statistical significanceno p-value reported

Oncoplastic BCS demonstrated a lower relative risk of positive margins compared to standard BCS (RR 0.7, 95% CI 0.4–1.2), although this did not reach statistical significance (Fig. 4 ).

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showed a trendno p-value reported

Yet, we also showed a trend towards a lower risk of positive margins in ILC patients after oncoplastic BCS compared with standard BCS, especially in patients with larger tumor sizes.

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