Similarly, in the I‐SPY trial [ 12 ], having sufficient levels of vitamin D was linked to higher odds of pCR compared to individuals with insufficient vitamin D levels, although this association did not reach statistical significance ( p = 0.25, OR: 1.54; 95% CI, 0.49–4.80).
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Vitamin D Supplementation During Neoadjuvant Chemotherapy for Breast Cancer Improves Pathological Complete Response: A Prospective Randomized Clinical Trial.
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The sentences
Although this effect is not significant for axillary pCR, there is an almost significant correlation.
Nevertheless, the present analysis shows that there is an important trend for improved survival with vitamin‐D supplementation.