Bupropion decreases plasma levels of asymmetric dimethylarginine and ameliorates renal injury by modulation of Ddah1, Oatp4c1, Oct2, and Mate1 in rats with adenine-induced chronic renal injury.

Front Pharmacol · 2025 · PMC12138378 · PMID 40474975

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

A 615.73% increase in CL, a 2085.67% increase in V ss , and a 66.48% decrease in C max were also observed; however, these changes did not reach statistical significance ( Table 2 ; Figure 9B ).

also in 111,027 other papers

failed to reach statistical significanceno p-value reported

Cumulative amount of ADMA and Cre excreted in urine and CL renal of ADMA and Cre increased by 28.98% 24.08%,35.04% and 114.60%, respectively, but they failed to reach statistical significance.

also in 6,035 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.