Barely Significant
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Evaluation of efficacy and safety of targeted therapy and immune checkpoint inhibitors in metastatic colorectal cancer.

World J Gastrointest Oncol · 2025 · PMC12142254 · PMID 40487962

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showed a trendno p-value reported
Although the median OS showed a trend toward improvement in the combination group, the difference was insignificant.

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OS non-significance: In all three analyses, OS did not reach statistical significance, though the combination of TT and immunotherapy did show a trend toward longer median OS.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.