Interestingly, male KO mice showed a trend towards higher prostanoid levels in sWAT (Fig. 5 B, C and Table.
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Alkylglycerol monooxygenase represses prostanoid biosynthesis in a sex-dependent manner.
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Similar to our findings in non-infected mice and murine BMDMs, Agmo deletion had little effect on cytokine transcription in adipose tissue under infection, except for a clear trend towards higher Il-1b and Tnfa levels in female KO BAT samples (Fig.