Isomeric 3-Pyridinylmethylcoumarins Differ in Erk1/2-Inhibition and Modulation of BV2 Microglia-Mediated Neuroinflammation.

Molecules · 2025 · PMC12156390 · PMID 40509339

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highly significantno p-value reported

In higher concentrations, highly significant results were obtained.

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a slight trendno p-value reported

X7732 showed a slight trend to reduce Erk1/2 phosphorylation while X7625 did not modulate Erk phosphorylation.

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

X7732 showed a trend toward reduced cell viability at the highest concentration, although this effect did not reach statistical significance.

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