Barely Significant
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Impact of body composition on pathological response to neoadjuvant immunotherapy in dMMR/MSI-H colorectal cancer.

Front Immunol · 2025 · PMC12162661 · PMID 40519904

2
hedged sentences
0.0140
closest p · 0.3× alpha
0.0800
boldest claim

The sentences

showed a trendp=0.014actually significant
Particularly, VAT showed a trend towards lower values in the TRG3 group (no tumor regression) (p=0.014), suggesting association between decreased visceral depots and non-responsive tumors.

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a near-significant trendp = 0.080so close (0.05 < p ≤ 0.1)
Total adipose tissue (TAT) showed a near-significant trend (OR = 1.01, 95% CI: 0.99-1.02, p = 0.080), indicating a potential but non-significant association ( Table 2 ).

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