Negative associations of age and lifestyle factors with the antibody response to the COVID-19 vaccine BNT162b2 in health workers from Spain.

With regard to the neutralizing antibody titers, the following results were observed ( Table 2 ): 1) for the Alpha variant, there was a negative association with age and smoking, although this did not reach statistical significance; 2) for the Beta variant, there was a borderline non-significant negative association with smoking habit; and 3) for the wild-type variant, there was no association.

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