RAMP1-dependent hormonal regulation of CGRP and its receptor in the trigeminal ganglion.

J Headache Pain · 2025 · PMC12172354 · PMID 40528180

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)

did not reach statistical significanceno p-value reported

Interestingly, 5-aza-dC treatment upregulated Ramp1 expression and showed a trend toward downregulation of Calca ( p = 0.08), although this did not reach statistical significance (Fig. 6 C + D).

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