Association Between Lycopene and Metabolic Disease Risk and Mortality: Systematic Review and Meta-Analysis.

Life (Basel) · 2025 · PMC12194687 · PMID 40566597

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

a clear trendp = 0.054so close (0.05 < p ≤ 0.1)

Although not statistically significant, a clear trend of patients with DM having lower lycopene levels than the control group was observed (MD = −0.09, 95% CI: −0.19 to 0.00, p = 0.054).

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did not reach statistical significanceno p-value reported

[ 52 ] (2007) substantially influenced heterogeneity; its removal dramatically reduced the I 2 from 93.9% to 5.0% and shifted the effect estimate to MD = 17.9 [−12.6 to 48.5], though the corresponding difference still did not reach statistical significance ( Figure S4 ).

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