Reirradiation for recurrent glioblastoma: the significance of the residual tumor volume.

J Neurooncol · 2025 · PMC12198277 · PMID 40310485

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did not reach statistical significanceno p-value reported

Although chemotherapy provided an additive effect, it did not reach statistical significance [ 27 ].

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showed a trendno p-value reported

In a study of 147 patients with recurrent high-grade gliomas, including 105 glioblastomas (71%), hypofractionated irradiation with a single dose of 3.5 Gy up to a median total dose of 35 Gy showed a trend toward better overall survival with doses above 35 Gy [ 26 ].

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