Impaired splicing machinery in craniopharyngiomas unveils PRPF8 and RAVER1 as novel biomarkers and therapeutic targets.

Acta Neuropathol Commun · 2025 · PMC12205502 · PMID 40581690

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

In contrast, we found that PRPF8 and RAVER1 mRNA levels were significantly upregulated in recurrent ( n = 13) relative to primary ACP ( n = 10) tumours and PRPF40A showed a trend towards increased expression that did not reach statistical significance (Fig. 4 B).

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