Factors Influencing Leaks in Primary Intestinal Anastomoses: An Observational Study.

Cureus · 2025 · PMC12208276 · PMID 40589695

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0910

boldest claim

The sentences

a trend toward significancep = 0.053so close (0.05 < p ≤ 0.1)

Although CRP levels on postoperative day 3 showed a trend toward significance (p = 0.053), the confidence interval narrowly included 1.00, indicating borderline predictive value.

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a near-significant trendp = 0.091so close (0.05 < p ≤ 0.1)

While CRP had a near-significant trend (p = 0.091), it did not reach conventional thresholds for significance, suggesting it may still hold predictive potential when combined with other factors, as shown in Table 9 .

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did not reach statistical significanceno p-value reported

Although smoking did not reach statistical significance in our cohort, current smokers showed a higher trend of AL, echoing findings by Kim et al. and others who demonstrated impaired healing due to vasoconstriction and tissue hypoxia in smokers [ 11 , 14 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.