Sd-021, derivatives of decursin, inhibits tumorigenesis in NSCLC by inhibiting the EGFR/STAT3 signaling pathway.

Sci Rep · 2025 · PMC12215028 · PMID 40594251

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did not reach statistical significanceno p-value reported

Although cleaved caspase-8 signals were detectable in HCC827 and H460 cells following Sd-021 treatment, these did not reach statistical significance upon quantification.

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showed a trendno p-value reported

Notably, in H460 cells, Sd-021 treatment resulted in a statistically significant difference compared to decursin, whereas in HCC827 cells, the changes in the sub-G1/G0 and G2/M phases showed a trend but were not statistically significant (Fig. 3 A).

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