Stimulation of corticospinal neurons by optogenetic cAMP inductions promotes motor recovery after spinal cord injury in female rats via raphespinal tract modulation.

Nat Commun · 2025 · PMC12216545 · PMID 40592902

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0.0800

closest p · 1.6× alpha

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boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)

Consistently, HPLC determination of 5-HT levels in spinal cord extracts showed a trend toward higher caudal-to-rostral 5-HT concentrations in bPAC animals compared to control (0.51 ± 0.27vs.0.14 ± 0.11 μM/mg protein, respectively; p = 0.08, Mann–Whitney test, Fig. 5G ).

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did not reach statistical significanceno p-value reported

A similar trend was observed caudal to the lesion, although it did not reach statistical significance.

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