mRNA ratios of AR to ESR1 and PGR distinguish breast cancer subtypes based on public datasets and experimental models.

Contrary to AR/ESR1 ratio, higher AR/PGR ratio values (≥ 1.54) did not show a clear trend to be associated with the HER2-enriched subtype.

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Here when comparing luminal tumors (ER+), the association between BC subtypes (both IHC-surrogate and molecular) and ratio values showed that tissues from BC patients with AR/PGR ≥ 1.54 have a significant trend to be classified as Luminal B when compared to Luminal A tumors (Figs. 3 A and 4 ).

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