Novel modified blumgart anastomosis reduces clinically relevant pancreatic fistula after pancreaticoduodenectomy: a retrospective study using inverse probability of treatment weighting.

Front Surg · 2025 · PMC12222157 · PMID 40611923

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0630

boldest claim

The sentences

highly significantp < 0.001actually significant

The advantage in PJ anastomosis time remained highly significant (21.1 ± 5.5 vs. 29.0 ± 7.4 min, p < 0.001), reflecting a 27.2% reduction in the time required to complete the anastomosis.

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showed a trendp = 0.063so close (0.05 < p ≤ 0.1)

Non-PDAC pathology also showed a trend toward increased risk (OR: 1.88, 95% CI: 0.98–3.76, p = 0.063).

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marginal significanceno p-value reported

Additionally, preoperative albumin < 35 g/L (OR: 1.91, 95% CI: 0.92–3.98, p = 0.082) and intraoperative blood loss ≥ 500 ml (OR: 1.92, 95% CI: 0.93–3.95, p = 0.076) demonstrated marginal significance.

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did not reach statistical significanceno p-value reported

Other complications, including biochemical leak, hemorrhage, bile leakage, pulmonary infection, intra-abdominal infection, and reoperation, showed lower incidence in the m-BPJ group, but the differences did not reach statistical significance after IPTW.

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