Vascular architecture mapping reveals sex-specific changes in cerebral microvasculature with aging.

However, these results did not reach statistical significance after correcting for multiple comparisons.

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While regional cerebral blood volume increased with age in both grey and white matter, women showed a trend towards lower rCBV compared to age-matched males in thalamus and hippocampus, regions that have been found to show sex differences in volume and tissue density ( Honarpisheh & McCullough, 2019 ; Ruigrok et al., 2014 ).

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