Women who underwent early PBO also showed a trend of greater tau deposition compared to the referent women after adjusting for age (PBO p = 0.13), or for age and APOE ε4 status (PBO p = 0.16), but this difference did not reach statistical significance (Table 2 ).
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Premenopausal bilateral oophorectomy and Alzheimer's disease imaging biomarkers later in life.
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0.1300