Derisking Phase II Clinical Trials in Heart Failure: A Position Paper from JACC: Basic to Translational Science and the Heart Failure Collaboratory.

JACC Basic Transl Sci · 2025 · PMC12235394 · PMID 40436529

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closest p

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did not reach statistical significanceno p-value reported

In some cases, where the primary endpoint did not reach statistical significance the analysis plan may identify a finding with a P value that is “nominally” statistically significant.

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nominally significantno p-value reported

Nominally significant P values may also arise from analyses of other endpoints where control of the type-I error rate was not planned.

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