Mapping the Gut Microbiota Composition in the Context of Raltegravir, Dolutegravir, and Bictegravir-A Scoping Review.

Int J Mol Sci · 2025 · PMC12250284 · PMID 40650144

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showed a trendno p-value reported

Microbial composition showed a trend towards increased Prevotella-9 and decreased Phascolarctobacterium and Bacteroides after switching from PI or efavirenz to raltegravir, though these changes could not be directly attributed to either prior regimen.

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did not reach statistical significanceno p-value reported

Participants in the raltegravir arm exhibited significantly higher zonulin levels compared to those in the other treatment groups, while increases in I-BABP and LBP levels were observed but did not reach statistical significance.

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