The results of principal component analysis (PCA) showed that the control and Lurasidone-treated samples showed a significant trend of separation in the PC1 and PC2 dimensions ( Figure 3A ).
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Lurasidone induces developmental toxicity and behavioral impairments in zebrafish embryos.
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The serotonergic system showed more complex alterations, with changes in both 5-HIAA and 5-HTP levels, but these changes did not reach statistical significance.