Long-term outcomes after Ivor-Lewis versus McKeown esophagectomy with two-field lymphadenectomy for resectable middle or lower thoracic esophageal squamous cell carcinoma.

Langenbecks Arch Surg · 2025 · PMC12267382 · PMID 40668435

Europe PMC DOI

hedged sentences

0.0610

closest p · 1.2× alpha

0.0840

boldest claim

The sentences

showed a trendP = 0.061so close (0.05 < p ≤ 0.1)

As for other subgroups, only among cases with pStage ≥ IIIA, McKeown esophagectomy showed a trend towards longer mOS(49.0 vs 28.0 months, P = 0.061) and mDFS(42.5 vs 18.5 months, P = 0.055), although statistical significance was not reached(Supplementary Table 1).

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did not reach statistical significanceP = 0.084so close (0.05 < p ≤ 0.1)

Despite overall survival rates remained similar, a trend towards a higher recurrence rate was observed in the Ivor-Lewis group after PSM, although this difference did not reach statistical significance(P = 0.084).

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