Association between white matter hyperintensities and gray matter volume in cerebral small vessel disease: insights from periventricular and deep white matter lesions.

Front Neurol · 2025 · PMC12283301 · PMID 40703777

Europe PMC DOI

hedged sentences

0.0410

closest p · 0.8× alpha

0.0410

boldest claim

The sentences

marginally significantp = 0.041actually significant

Comparison of GM_n across different DWMH Fazekas scores Kruskal–Wallis testing revealed a marginally significant group-level difference in GM_n across DWMH Fazekas scores ( p = 0.041).

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showed a trendno p-value reported

Although patients with DWMH score of 3 showed a trend toward reduced GM_n in univariate analysis, the association did not remain significant after adjusting for age and vascular risk factors.

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did not reach statistical significanceno p-value reported

However, subsequent post hoc pairwise comparisons did not reach statistical significance after FDR correction.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.