Unraveling resistance mechanisms to the novel nucleoside analog RX-3117 in lung cancer: insights into DNA repair, cell cycle dysregulation and targeting PKMYT1 for improved therapy.

At the protein level, both DCTPP1 and NUDT1 exhibited a trend toward increased expression compared to parental cells; however, these changes did not reach statistical significance.

also in 111,027 other papers

These analyses showed a trend towards a reduced sensitivity in most models, as reported in Supplementary Table 2 .

also in 53,322 other papers