CPAP improves regional lung strain rate and diaphragm velocity of relaxation in experimental self-inflicted lung injury.

In the former, there was a clear trend toward higher aeration in the CPAP group, a predictable consequence of PEEP use [ 25 ].

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In contrast with the Control group, the CPAP group resulted in: (1) higher oxygenation and lower respiratory rate, nasal flaring, inspiratory and expiratory muscle activation, and V E at T3; (2) lower global and regional tidal ventilation at T0; (3) lower regional volumetric strain at T0; (4) lower regional lung strain rate at T0 and T3 during the inspiratory phase; (5) lower regional lung strain rate at T3 during the expiratory phase; (6) higher muscle area in the diaphragm morphometric analysis; and (7) a marked trend to higher aeration in the lung morphometric analysis.

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