Interestingly, RSV → PBS female mice also showed a trend for increased inflammation ( Fig 6A ).
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Early-life RSV infection modulates innate immune events, preferentially enhancing allergen-induced type 2 lung inflammation in females.
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Similar increases in IL-13-expressing KLRG1 – ILC2s were also apparent in RSV → PBS female mice, though the increase did not reach statistical significance ( Fig 6D ).