Barely Significant
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Clinical Outcomes of Common Femoral Thromboendarterectomy for Lower-Extremity Arterial Disease: Differences Between Chronic Limb-Threatening Ischemia and Intermittent Claudication.

Vasc Specialist Int · 2025 · PMC12311306 · PMID 40739708

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closest p · 1.0× alpha
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boldest claim

The sentences

showed a trendP=0.051so close (0.05 < p ≤ 0.1)
Multivariable analysis revealed that CLTI itself was not an independent predictor of mortality; rather, a worse systemic status (e.g., higher American Society of Anesthesiologists classification) showed a trend toward poorer outcomes (P=0.051).

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Interestingly, ASA class showed a higher HR of 4.50 (95% CI 1.00-20.31; P=0.051), suggesting a potential impact of systemic status on overall survival, although the association did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.