Barely Significant
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Trends in surgical indications and causative diagnoses in enucleation from 2007 to 2022.

Sci Rep · 2025 · PMC12317067 · PMID 40751077

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a negative trendno p-value reported
Regarding indications for enucleation there is a negative trend for “painful blind eye” and “malignant tumor”.

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While we observed a tendency toward longer intervals from diagnosis to enucleation in more recent years, this trend did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.