Delineation of the Human Germinal Centre Immune Landscape Using Multiplex Imaging Analysis.

Immunology · 2025 · PMC12318895 · PMID 40421691

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did not reach statistical significanceno p-value reported

Both CD4 hi IL21 hi T and CD4 hi CXCL13 hi T normalised cell counts were higher in tonsillar follicles (although CD4 hi CXCL13 hi results did not reach statistical significance) compared to LNs (Figure 7C ).

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a clear trendno p-value reported

Estimation of the randomness of the calculated distance profiles (cross‐G function for the calculated minimum distance among two cell types) showed a clear trend for a higher degree of randomness for the distance profile between DZ B cells and CD3 hi PD1 hi CD57 hi CXCR3 lo compared to CD3 hi PD1 hi CD57 lo CXCR3 hi T FH cells in LNs (Figure 3D , lower panel).

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